In 2006, the Centers for Disease Control and Prevention (CDC) issued new recommendations for HIV testing that was to increase the early diagnosis of human immunodeficiency virus (HIV) infection by recommending it be a routine part of medical care. But were you aware that HIV is the most important known risk factor for the progression from latent tuberculosis infection (LTBI) to TB disease? Individuals testing positive for LTBI and HIV infection that are not treated for both conditions have a high risk of progressing from LTBI to TB disease. By clicking here, you can read more on this issue from information that will be included in the Pennsylvania Department of Health’s TB Manual.