The Annual Report to the Nation on the Status of Cancer was recently released and contains some good and bad news. The good news – mortality rates for lung cancer in the United States rapidly declined from 2001 to 2018. Among the bad news- age-standardized oral and pharyngeal cancer incidence rates increased during that period and pharyngeal mortality rates also increased for men but dropped slightly for women. The incidence of most smoking-related cancers (lung, larynx, bladder) has been declining in the U.S. largely due to the declining prevalence of smoking.